Benign prostatic hyperplasia (BPH) is a very disease that strikes many men due to the natural changes that occur as a man ages. Hormones, as well as risk factors including obesity, metabolic syndrome, insulin resistance, increased systemic inflammation, are all associated with BPH (Rakel, 2018). The most well-known supplement for BPH is Saw Palmetto. This supplement is antiandrogenic, antiproliferative and antiinflammatory (Rakel, 2018).
A study completed by Andriole et., al (2013) concluded there was no difference between Saw Palmetto and a placebo on the effect of the PSA level.
References:
Andriole, G. L., McCullum-Hill, C., Sandhu, G. S., Crawford, E. D., Barry, M. J., Cantor, A., & CAMUS Study Group. (2013). The effect of increasing doses of saw palmetto fruit extract on serum prostate specific antigen: analysis of the CAMUS randomized trial. The Journal of urology, 189(2), 486-492.
Rakel, D. (2018) Integrative medicine (4thEd.). Elsevier Saunders: Philadelphia.